| Date | Home | Away | Result |
|---|---|---|---|
| 3/21/26 12:00 PM | Toronto FC | Columbus Crew | --- |
| 3/21/26 3:30 PM | Philadelphia Union | Chicago Fire | --- |
| 3/21/26 5:15 PM | Nashville SC | Orlando City | --- |
| 3/21/26 6:30 PM | Charlotte FC | New York Red Bulls | --- |
| 3/21/26 6:30 PM | Atlanta United FC | D.C. United | --- |
| 3/21/26 7:30 PM | St. Louis City SC | New England Revolution | --- |
| 3/21/26 7:30 PM | Sporting Kansas City | Colorado Rapids | --- |
| 3/21/26 7:30 PM | FC Dallas | Houston Dynamo | --- |
| 3/21/26 7:45 PM | Austin FC | Los Angeles FC | --- |
| 3/21/26 9:30 PM | Vancouver Whitecaps | San Jose Earthquakes | --- |
| 3/22/26 12:00 PM | New York City FC | Inter Miami CF | --- |
| 3/22/26 12:00 PM | Cincinnati FC | CF Montreal | --- |
| 3/22/26 1:30 PM | Minnesota United FC | Seattle Sounders | --- |
| 3/22/26 3:45 PM | Portland Timbers | Los Angeles Galaxy | --- |
| 3/22/26 6:00 PM | San Diego FC | Real Salt Lake | --- |